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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: Hypoxemia exerts detrimental effects on the choroid plexuses and cerebrospinal fluid system in rats

Fig. 6Fig. 6

Cell death in the CPs and EL after applications of inhibitors. Panels A and B. typical images of the CP (6A) and EL (6B) following TUNEL staining after hypoxemia, with and without inhibition protocols prior to hypoxemia. Inhibitors were sEPOR (EPO signaling inhibition), Axitinib (VEGF signaling inhibition), and Etaner (Etanercept; TNFα signaling inhibition). Nuclei are stained with DAPI (blue), while TUNEL-positive cells (indicating cell death) are shown in green. Scale bar: 50 μm. Arrows in 6B highlight the EL. Graphs in A and B the graphs to the right of each inhibition protocol display raw data for each group alongside the mean ± SD. Asterisks (*) indicate significant differences between the experimental group and its corresponding vehicle: *p < 0.05, **p < 0.01, ***p < 0.001

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