Table 1 Characteristics of included cases (N = 19)
From: Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease
Neuropathological Outcomes | CNI (n = 9) | AD (n = 10) |
|---|---|---|
Age (y, mean ± SD) | 86.7 ± 6.0 | 82.2 ± 9.0 |
PMI (h, mean ± SD) | 3.6 ± 3.4 | 3.9 ± 1.5 |
Duration | ||
Gender (M/F) | 4/5 | 3/7 |
Race | White | White |
Education (y, mean ± SD) | 16.1 ± 1.5 | 14.0 ± 2.9 |
APOE allele status | ||
e3/e3 | 3 | 4 |
e2/e3 | 3 | 0 |
e3/e4 | 2 | 4 |
e4/e4 | 1 | 2 |
CDRGLOB | 0–0 | 0.5–3 |
MMSE score (mean ± SD) | 29.1 ± 1.3 | 18.0 ± 9.5 |
Braak staging | I–III | V–VI |
CAA | 1–3 | 1–3 |
Co-morbidities | ||
Cancer | 5 | 3 |
Smoking | 4 | 3 |
Heart attack | 2 | 0 |
Atrial fibrillation | 1 | 1 |
Hypertension | 5 | 4 |
Transient ischemic attack | 0 | 1 |
Cardiac arrythmia | 2 | 1 |
Diabetes | 0 | 1 |
Cerebral atrophy | Abs/mild/mod | Abs/mild/mod |