Table 5 Variations in microvascular diameters with neuropathological, cognitive, and biochemical predictors for CNI and AD Patients
From: Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease
Response | Predictor | χ2 | Raw p value | Adjusted p valuea | R2 |
|---|---|---|---|---|---|
COL-IV diameter (μm) | Braak stage | 43.082 (4) | < 0.001 | < 0.001 | 0.041 |
COL-IV diameter (μm) | NP scores | 11.108 (1) | < 0.001 | 0.005 | 0.057 |
COL-IV diameter (μm) | Brain Aβ40 levels (ng/mg brain tissue) | 13.353 (1) | < 0.001 | 0.002 | 0.107 |
Fibrinogen diameter (μm) | Braak stage | 26.669 (4) | < 0.001 | < 0.001 | 0.111 |
Fibrinogen diameter (μm) | Neuritic plaque frequency | 7.600 (1) | 0.006 | 0.042 | 0.044 |
vWF diameter (μm) | CAA severity score | 11.202 (2) | 0.004 | 0.031 | 0.041 |
vWF diameter (μm) | Brain Aβ40 levels (ng/mg brain tissue) | 9.274 (1) | 0.002 | 0.031 | 0.028 |