Table 6 Variations in peripheral biomarkers with neuropathological, cognitive, and biochemical outcomes for CNI and AD patients
From: Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease
Response | Predictor | Statistica | Raw p value | Adjusted p valueb | R2 |
|---|---|---|---|---|---|
Braak stage | Plasma S100β levels (pg/mL) | 11.277 (1) | < 0.001 | 0.008 | 0.644 |
Brain Aβ40 levels (ng/mg brain tissue) | Plasma S100β levels (pg/mL) | 9.899 (1,11) | 0.009 | 0.046 | 0.406 |
CDR scores | Plasma MMP-2 levels (ng/mL) | 6.609 (1) | 0.010 | 0.046 | 0.420 |
Braak stage | Plasma MMP-9 levels (ng/mL) | 7.757 (1) | 0.005 | 0.036 | 0.499 |