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Table 7 Model comparisons of peripheral biomarkers vs. consensus diagnosis for CNI and AD patients

From: Plasma S100β is a predictor for pathology and cognitive decline in Alzheimer’s disease

Predictor

AICc

Probabilitya

χ2

Raw p value

Adjusted p valuea

R2

Plasma S100β levels (pg/mL)

5.200

0.915

17.323 (1)

 < 0.001

0.001

1.000

Plasma NSE levels (ng/mL)

11.918

0.032

10.605 (1)

0.001

0.009

0.637

Plasma MMP-2 levels (ng/mL)

10.994

0.051

11.529 (1)

 < 0.001

0.008

0.683

Plasma MMP-9 levels (ng/mL)

16.961

0.003

5.562 (1)

0.018

0.073

0.365

  1. aProbability of the model being “correct” vs. other models in set, derived from ΔAICc (Burnham & Anderson, 2002)
  2. bAdjusted by Benjamni-Hochberg FDR