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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Kidins220-deficient hydrocephalus mice exhibit altered glial phenotypes and AQP4 differential regulation in the retina and optic nerve, with preserved retinal ganglion cell survival

Fig. 1

Obstructive hydrocephalus in Kidins220f/f deficient mice where retinas have been analyzed. Representative in vivo brain coronal view of T2-weighted (T2-W) magnetic resonance images (MRI) showing lateral and third ventricles (LVs + TV; left panels), aqueduct of Sylvius (SA; central panels) and fourth ventricle (FV; right panels) of 2-month-old WT and Kidins220f/f male mice. Graphs represent the quantification of the volume (mm3) of the lateral and third ventricles (LV + TV), Sylvius aqueduct (SA) and fourth ventricle (FV) in WT and Kidins220f/f mice. Each data point denotes one individual. Data are mean ± s.e.m. and were analyzed by two-tailed unpaired Student t-test. **p < 0.01, ****p < 0.0001. Scale bar 1 mm

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