Enlarged choroid plexus is linked with poorer physical function in rural older adults: a population-based study

Table 3 Associations of choroid plexus volume with white matter hyperintensity volume and ventricular volume (n = 1165)

MRI markers	β coefficient (95% CI), MRI markers
MRI markers	Model 1	Model 2
WMH volume (ml)
Total WMH volume	1.48 (0.81, 2.16) ^**	1.23 (0.60, 1.95) ^**
Periventricular WMH volume	1.41 (0.78, 2.05) ^**	1.21 (0.58, 1.84) ^**
Deep WMH volume	0.07 (-0.02, 0.16)	0.07 (-0.02, 0.16)
Ventricular volume (ml)
Lateral ventricular volume	4.94 (4.37, 5.52) ^**	4.67 (4.11, 5.23) ^**
Inferior lateral ventricles volume	0.34 (0.30, 0.39) ^**	0.33 (0.28, 0.37) ^**

Abbreviations: MRI, magnetic resonance imaging; WMH, white matter hyperintensity; CI, Confidence Interval; SPPB, Short Physical Performance Battery
Note: Data were β coefficients (95% confidence intervals) of volumetric measures of MRI markers associated with per 1-ml increase in choroid plexus volume derived from two different models. Model 1 was controlled for age, sex, education, and total intracranial volume; model 2 was additionally adjusted for smoking, alcohol intake, body mass index, physical exercise, hypertension, diabetes, dyslipidemia, APOE genotype, stroke, and disproportionately enlarged subarachnoid-space hydrocephalus
^*P < 0.05, ^**P < 0.01

ISSN: 2045-8118